3HL8
Crystal structure of exonuclease I in complex with inhibitor BCBP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Exodeoxyribonuclease I | polymer | 482 | 55510.6 | 1 | UniProt (P04995) Pfam (PF00929) Pfam (PF08411) | Escherichia coli | Exonuclease I, DNA deoxyribophosphodiesterase, dRPase |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | (5R)-3-tert-butyl-1-(6-chloro-1,3-benzothiazol-2-yl)-4,5-dihydro-1H-pyrazol-5-ol | non-polymer | 307.8 | 1 | Chemie (BBP) | |||
| 4 | D, E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 5 | F, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | I (A) | water | water | 18.0 | 492 | Chemie (HOH) |
Sequence modifications
A: 1 - 475 (UniProt: P04995)
| PDB | External Database | Details |
|---|---|---|
| Asp 472 | Glu 472 | SEE REMARK 999 |
| Glu 476 | - | expression tag |
| His 477 | - | expression tag |
| His 478 | - | expression tag |
| His 479 | - | expression tag |
| His 480 | - | expression tag |
| His 481 | - | expression tag |
| His 482 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55510.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 674.6 | |
| All* | Total formula weight | 56185.1 |
