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3HKW

HCV NS5B genotype 1a in complex with 1,5 benzodiazepine inhibitor 6

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CNS5B RNA-dependent RNA polymerasepolymer58164319.73Pfam (PF00998)
UniProt (by SIFTS) (P26664)
In PDB
Hepatitis C virus subtype 1a
2A, B, C(11S)-10-[(2,5-dimethyl-1,3-oxazol-4-yl)carbonyl]-11-{2-fluoro-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}-3,3-dimethyl-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxidenon-polymer581.73Chemie (IX6)
3C, A, BSULFATE IONnon-polymer96.119Chemie (SO4)
4A, BGLYCEROLnon-polymer92.16Chemie (GOL)
5waterwater18.01570Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight192959.1
Non-Polymers*Number of molecules28
Total formula weight4122.7
All*Total formula weight197081.9
*Water molecules are not included.

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PDB entries from 2024-07-24

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