Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| B | 0039694 | biological_process | viral RNA genome replication |
| C | 0003723 | molecular_function | RNA binding |
| C | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| C | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE IX6 A 579 |
| Chain | Residue |
| A | PHE193 |
| A | TYR448 |
| A | GLY449 |
| A | SER556 |
| A | HOH821 |
| A | HOH880 |
| A | CYS366 |
| A | SER367 |
| A | ARG386 |
| A | ASN411 |
| A | MET414 |
| A | PHE415 |
| A | GLU446 |
| A | ILE447 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 580 |
| Chain | Residue |
| A | ASN24 |
| A | ARG436 |
| A | HOH801 |
| A | HOH1164 |
| A | HOH1170 |
| C | LYS209 |
| C | ARG380 |
| C | TYR382 |
| C | HOH1409 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 581 |
| Chain | Residue |
| A | LYS209 |
| A | ARG380 |
| A | TYR382 |
| A | HOH605 |
| A | HOH890 |
| B | ASN24 |
| B | ARG436 |
| B | HOH672 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 582 |
| Chain | Residue |
| A | ARG32 |
| A | HIS33 |
| A | GLU237 |
| A | GLN241 |
| A | LYS254 |
| A | HOH726 |
| A | HOH955 |
| A | HOH1554 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 583 |
| Chain | Residue |
| A | ARG505 |
| A | ARG531 |
| A | THR532 |
| A | HOH640 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 584 |
| Chain | Residue |
| A | GLU440 |
| A | GLY516 |
| A | ARG517 |
| A | HOH924 |
| A | HOH1515 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 585 |
| Chain | Residue |
| A | ARG48 |
| A | LYS51 |
| A | ARG222 |
| A | CYS223 |
| A | HOH947 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 586 |
| Chain | Residue |
| A | ASN28 |
| A | ARG32 |
| A | HIS34 |
| A | VAL251 |
| A | HOH609 |
| A | HOH661 |
| A | HOH727 |
| A | HOH1159 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 587 |
| Chain | Residue |
| A | SER29 |
| A | ASP244 |
| A | ARG250 |
| A | PRO495 |
| A | ARG503 |
| A | HOH779 |
| A | HOH836 |
| A | HOH1119 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 588 |
| Chain | Residue |
| A | HIS475 |
| A | SER476 |
| A | HOH845 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 589 |
| Chain | Residue |
| A | GLN58 |
| A | LEU60 |
| A | SER231 |
| A | HOH883 |
| A | HOH891 |
| site_id | BC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE IX6 B 579 |
| Chain | Residue |
| B | PHE193 |
| B | ARG200 |
| B | CYS366 |
| B | SER367 |
| B | SER368 |
| B | ARG386 |
| B | ASN411 |
| B | MET414 |
| B | PHE415 |
| B | GLU446 |
| B | ILE447 |
| B | TYR448 |
| B | GLY449 |
| B | SER556 |
| B | HOH773 |
| B | HOH897 |
| B | HOH900 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 580 |
| Chain | Residue |
| B | HOH846 |
| B | HOH1181 |
| B | HOH1212 |
| B | HOH1478 |
| B | ARG32 |
| B | HIS33 |
| B | GLU237 |
| B | GLN241 |
| B | LYS254 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 581 |
| Chain | Residue |
| B | ARG48 |
| B | LYS51 |
| B | ARG222 |
| B | CYS223 |
| B | HOH1383 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 582 |
| Chain | Residue |
| A | HIS374 |
| A | ARG380 |
| B | HIS402 |
| B | GLN438 |
| B | GOL585 |
| B | HOH738 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 583 |
| Chain | Residue |
| B | GLU440 |
| B | GLY516 |
| B | ARG517 |
| B | HOH803 |
| B | HOH1506 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 584 |
| Chain | Residue |
| B | ARG505 |
| B | VAL530 |
| B | ARG531 |
| B | THR532 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 585 |
| Chain | Residue |
| B | GLU398 |
| B | ASN406 |
| B | TRP408 |
| B | VAL432 |
| B | ARG436 |
| B | GLN438 |
| B | SO4582 |
| B | HOH780 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 586 |
| Chain | Residue |
| B | SER29 |
| B | ASP244 |
| B | ARG250 |
| B | PRO495 |
| B | ARG503 |
| B | HOH699 |
| B | HOH912 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 587 |
| Chain | Residue |
| B | HIS475 |
| B | SER476 |
| B | HOH719 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 588 |
| Chain | Residue |
| B | SER39 |
| B | ASN142 |
| B | GLU143 |
| B | VAL144 |
| B | TRP397 |
| B | HOH1060 |
| site_id | CC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE IX6 C 579 |
| Chain | Residue |
| C | PHE193 |
| C | CYS366 |
| C | SER367 |
| C | SER368 |
| C | ARG386 |
| C | ASN411 |
| C | MET414 |
| C | PHE415 |
| C | GLU446 |
| C | ILE447 |
| C | TYR448 |
| C | GLY449 |
| C | SER556 |
| C | HOH720 |
| C | HOH884 |
| C | HOH945 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 580 |
| Chain | Residue |
| C | ARG32 |
| C | HIS33 |
| C | LYS69 |
| C | LYS72 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 581 |
| Chain | Residue |
| C | ARG48 |
| C | LYS51 |
| C | ARG222 |
| C | CYS223 |
| C | HOH973 |
| site_id | CC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 582 |
| Chain | Residue |
| A | HIS402 |
| A | GLN438 |
| A | HOH838 |
| A | HOH892 |
| A | HOH979 |
| A | HOH1125 |
| C | HIS374 |
| C | ARG380 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 583 |
| Chain | Residue |
| C | ARG505 |
| C | VAL530 |
| C | ARG531 |
| C | THR532 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 584 |
| Chain | Residue |
| C | SER431 |
| C | SER506 |
| C | VAL507 |
| C | LYS510 |
| C | HOH683 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 585 |
| Chain | Residue |
| C | GLU440 |
| C | LEU457 |
| C | GLY516 |
| C | ARG517 |
| C | HOH696 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 354 |
| Details | Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P26663","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"UniProtKB","id":"P26662","evidenceCode":"ECO:0000250"}]} |
