3HK0
Crystal Structure of the RA and PH Domains of Grb10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Growth factor receptor-bound protein 10 | polymer | 256 | 29500.7 | 2 | UniProt (Q13322) Pfam (PF21989) Pfam (PF00788) Pfam (PF00169) | Homo sapiens (human) | GRB10 adapter protein, Insulin receptor-binding protein Grb-IR |
| 2 | C (A) | THIOCYANATE ION | non-polymer | 58.1 | 1 | Chemie (SCN) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, B: 106 - 357 (UniProt: Q13322)
| PDB | External Database | Details |
|---|---|---|
| Gly 102 | - | expression tag |
| Ser 103 | - | expression tag |
| His 104 | - | expression tag |
| Met 105 | - | expression tag |
| Ser 145 | Cys 203 | engineered mutation |
| Ser 212 | Cys 270 | engineered mutation |
| Ser 232 | Cys 290 | engineered mutation |
| Ala 270 | Lys 328 | engineered mutation |
| Ala 271 | Glu 329 | engineered mutation |
| Ser 331 | Cys 389 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59001.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 58.1 | |
| All* | Total formula weight | 59059.5 |
