3HJU

Crystal structure of human monoglyceride lipase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Monoglyceride lipase	polymer	342	37698.1	2	UniProt (Q99685) Pfam (PF12146)	Homo sapiens (human)	Monoacylglycerol lipase, MAGL, MGL, Lysophospholipase homolog, Lysophospholipase-like, HU-K5
2	C, D (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	E, F (A, B)	water	water		18.0	177	Chemie (HOH)

Sequence modifications

A, B: 2 - 303 (UniProt: Q99685)

PDB	External Database	Details
Met -17	-	expression tag
Arg -16	-	expression tag
Gly -15	-	expression tag
Ser -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Gly -7	-	expression tag
Ala -6	-	expression tag
Gly -5	-	expression tag
Asp -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Pro -1	-	expression tag
Glu 0	-	expression tag
Phe 1	-	expression tag
Leu 304	-	expression tag
Glu 305	-	expression tag
Val 306	-	expression tag
Asp 307	-	expression tag
Leu 308	-	expression tag
Gln 309	-	expression tag
Gly 310	-	expression tag
Asp 311	-	expression tag
His 312	-	expression tag
Gly 313	-	expression tag
Leu 314	-	expression tag
Ser 315	-	expression tag
Ala 316	-	expression tag
Trp 317	-	expression tag
Ser 318	-	expression tag
His 319	-	expression tag
Pro 320	-	expression tag
Gln 321	-	expression tag
Phe 322	-	expression tag
Glu 323	-	expression tag
Lys 324	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75396.1
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	75580.3

*Water molecules are not included.