3HI7
Crystal structure of human diamine oxidase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Amiloride-sensitive amine oxidase | polymer | 731 | 83463.8 | 2 | UniProt (P19801) Pfam (PF02727) Pfam (PF02728) Pfam (PF01179) In PDB | Homo sapiens (human) | Diamine oxidase, DAO, Amiloride-binding protein, ABP, Histaminase, Kidney amine oxidase, KAO |
| 2 | C | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 3 | D, E, F, G, H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 4 | A, B | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) | |||
| 5 | A, B | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 6 | A, B | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 1136 | Chemie (HOH) |
Sequence modifications
A, B: 21 - 751 (UniProt: P19801)
| PDB | External Database | Details |
|---|---|---|
| Arg 21 | Pro 21 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 166927.6 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2708.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 840.0 | |
| All* | Total formula weight | 170476.1 |
