3HI1

Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	G, J	Glycoprotein 120	polymer	321	35962.9	2	UniProt (P35961) Pfam (PF00516) In PDB	Human immunodeficiency virus type 1 (HIV-1)	gp120, SU
2	L, A	F105 Light Chain	polymer	215	23495.0	2	Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (Q6PIL8) In PDB	Homo sapiens (human)
3	H, B	F105 Heavy Chain	polymer	225	23844.8	2		Homo sapiens (human)
4	J, G	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	27	Chemie (NAG)
5		water	water		18.0	78	Chemie (HOH)

Sequence modifications

G, J: 90 - 123 (UniProt: P35961)
G, J: 199 - 492 (UniProt: P35961)

PDB	External Database	Details
Gly 124	-	linker
Gly 198	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	166605.5
Non-Polymers*	Number of molecules	27
	Total formula weight	5972.6
All*	Total formula weight	172578.1

*Water molecules are not included.