3HI1

Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002250	biological_process	adaptive immune response
A	0002376	biological_process	immune system process
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
A	0019814	cellular_component	immunoglobulin complex
G	0019031	cellular_component	viral envelope
J	0019031	cellular_component	viral envelope
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0019814	cellular_component	immunoglobulin complex

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	Region: {"description":"CD4-binding loop","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	20
Details	Region: {"description":"V5"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	16
Details	Region: {"description":"V5","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	30
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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