3HHU

Human heat-shock protein 90 (HSP90) in complex with {4-[3-(2,4-dihydroxy-5-isopropyl-phenyl)-5-thioxo- 1,5-dihydro-[1,2,4]triazol-4-yl]-benzyl}-carbamic acid ethyl ester {ZK 2819}

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Heat shock protein HSP 90-alpha	polymer	224	25196.4	2	UniProt (P07900) Pfam (PF13589) In PDB	Homo sapiens (human)	HSP 86, Renal carcinoma antigen NY-REN-38
2	A, B	ethyl (4-{3-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-5-sulfanyl-4H-1,2,4-triazol-4-yl}benzyl)carbamate	non-polymer		428.5	2	Chemie (819)
3		water	water		18.0	564	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50392.8
Non-Polymers*	Number of molecules	2
	Total formula weight	857.0
All*	Total formula weight	51249.8

*Water molecules are not included.