3HHN

Crystal structure of class I ligase ribozyme self-ligation product, in complex with U1A RBD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (B, D)	U1 small nuclear ribonucleoprotein A	polymer	97	11209.1	2	UniProt (P09012) Pfam (PF00076)	Homo sapiens (human)	U1 snRNP protein A, U1A protein, U1-A
2	B, D (C, E)	Class I ligase ribozyme, self-ligation product	polymer	137	44168.3	2
3	AA, BA, CA, DA, E... (E, B, C)	MAGNESIUM ION	non-polymer		24.3	34	Chemie (MG)
4	MA, NA, OA, PA (B, C, D, E)	water	water		18.0	192	Chemie (HOH)

Sequence modifications

B, D: 2 - 98 (UniProt: P09012)

PDB	External Database	Details
His 31	Tyr 31	engineered mutation
Arg 36	Gln 36	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	110754.8
Non-Polymers*	Number of molecules	34
	Total formula weight	826.4
All*	Total formula weight	111581.1

*Water molecules are not included.