3HG4
Human alpha-galactosidase catalytic mechanism 3. Covalent intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Alpha-galactosidase A | polymer | 398 | 45394.5 | 2 | UniProt (P06280) Pfam (PF16499) Pfam (PF17450) In PDB | Homo sapiens (human) | Alpha-D-galactoside galactohydrolase, Alpha-D-galactosidase A, Melibiase |
| 2 | C, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 3 | D, G | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 4 | E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | A, B | 2-deoxy-2,2-difluoro-beta-D-lyxo-hexopyranose | non-polymer | 200.1 | 2 | Chemie (7JZ) | |||
| 6 | A, B | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | A, B | ACETIC ACID | non-polymer | 60.1 | 4 | Chemie (ACY) | |||
| 8 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 9 | B | beta-D-galactopyranose | non-polymer | 180.2 | 1 | Chemie (GAL) | |||
| 10 | water | water | 18.0 | 682 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90789.1 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3387.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1330.0 | |
| All* | Total formula weight | 95506.3 |
