3HF9

Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant modified by inhibitor GL1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, D, F, I...	Proteasome (Alpha subunit) PrcA	polymer	240	25972.0	28	UniProt (O33244) Pfam (PF00227) UniProt (by SIFTS) (P9WHU1) In PDB	Mycobacterium tuberculosis
2	H, C, E, G, J...	Proteasome (Beta subunit) PrcB	polymer	240	25300.3	28	UniProt (O33245) Pfam (PF00227) UniProt (by SIFTS) (P9WHU1) In PDB	Mycobacterium tuberculosis	Proteasome, beta subunit
3		water	water		18.0	137	Chemie (HOH)

Sequence modifications

A, B, D, F, I, K, M, O, Q, S, U, W, Y, 1, a, b, d, f, i, k, m, o, q, s, u, w, y, 3: 10 - 248 (UniProt: O33244)

PDB	External Database	Details
Met 9	-	initiating methionine

H, C, E, G, J, L, N, P, R, T, V, X, Z, 2, h, c, e, g, j, l, n, p, r, t, v, x, z, 4: 2 - 234 (UniProt: O33245)

PDB	External Database	Details
Ozt 1	-	insertion
His 235	-	expression tag
His 236	-	expression tag
His 237	-	expression tag
His 238	-	expression tag
His 239	-	expression tag
His 240	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	56
	Total formula weight	1435622.5
All*	Total formula weight	1435622.5

*Water molecules are not included.