3HF6
Crystal structure of human tryptophan hydroxylase type 1 with bound LP-521834 and FE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tryptophan 5-hydroxylase 1 | polymer | 290 | 33287.9 | 1 | UniProt (P17752) Pfam (PF00351) | Homo sapiens (human) | Tryptophan 5-monooxygenase 1 |
| 2 | B (A) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) PubChem (29936) | |||
| 3 | C (A) | 4-(4-amino-6-{[(1R)-1-naphthalen-2-ylethyl]amino}-1,3,5-triazin-2-yl)-L-phenylalanine | non-polymer | 428.5 | 1 | Chemie (LX0) PubChem (16678113) PubChem (45486489) PubChem (66649408) PubChem (68631117) PubChem (89582788) PubChem (89582789) | |||
| 4 | D (A) | water | water | 18.0 | 274 | Chemie (HOH) |
Sequence modifications
A: 104 - 393 (UniProt: P17752)
| PDB | External Database | Details |
|---|---|---|
| Ser 104 | Thr 104 | conflict |
| Arg 179 | Gln 179 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33287.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 484.3 | |
| All* | Total formula weight | 33772.2 |
