3HD7

HELICAL EXTENSION OF THE NEURONAL SNARE COMPLEX INTO THE MEMBRANE, spacegroup C 1 2 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Vesicle-associated membrane protein 2	polymer	91	10493.3	2	UniProt (P63045) Pfam (PF00957) In PDB	Rattus norvegicus (Rat)	VAMP-2, Synaptobrevin-2
2	B, F	Syntaxin-1A	polymer	109	12334.4	2	UniProt (P32851) Pfam (PF05739) In PDB	Rattus norvegicus (Rat)	Synaptotagmin-associated 35 kDa protein, P35A, Neuron-specific antigen HPC-1
3	C, G	Synaptosomal-associated protein 25	polymer	80	9312.4	2	UniProt (P60881) In PDB	Rattus norvegicus (Rat)	SNAP-25, Synaptosomal-associated 25 kDa protein, Super protein, SUP
4	D, H	Synaptosomal-associated protein 25	polymer	68	7753.6	2	UniProt (P60881) In PDB	Rattus norvegicus (Rat)	SNAP-25, Synaptosomal-associated 25 kDa protein, Super protein, SUP
5	A, E	glycylglycylglycine	non-polymer		189.2	3	Chemie (GGG)
6	C, D, E, F, H	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)

Sequence modifications

A, E: 30 - 116 (UniProt: P63045)

PDB	External Database	Details
Gly 26	-	expression tag
Ser 27	-	expression tag
His 28	-	expression tag
Met 29	-	expression tag

B, F: 183 - 288 (UniProt: P32851)

PDB	External Database	Details
Gly 180	-	expression tag
Ser 181	-	expression tag
His 182	-	expression tag

C, G: 7 - 83 (UniProt: P60881)

PDB	External Database	Details
Gly 4	-	expression tag
Ser 5	-	expression tag
His 6	-	expression tag

D, H: 141 - 204 (UniProt: P60881)

PDB	External Database	Details
Gly 137	-	expression tag
Ser 138	-	expression tag
His 139	-	expression tag
Met 140	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	79787.5
Non-Polymers*	Number of molecules	11
	Total formula weight	1336.0
All*	Total formula weight	81123.5

*Water molecules are not included.