3HC5
FXR with SRC1 and GSK826
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bile acid receptor | polymer | 232 | 27048.0 | 1 | UniProt (Q96RI1) Pfam (PF00104) In PDB | Homo sapiens (human) | Farnesoid X-activated receptor, Farnesol receptor HRR-1, Nuclear receptor subfamily 1 group H member 4, Retinoid X receptor-interacting protein 14, RXR-interacting protein 14 |
| 2 | B | Nuclear receptor coactivator 1 | polymer | 21 | 2650.0 | 1 | UniProt (Q15788) In PDB | ||
| 3 | A | 3-(6-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-1-benzothiophen-2-yl)benzoic acid | non-polymer | 538.4 | 1 | Chemie (82X) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A: 243 - 472 (UniProt: Q96RI1)
| PDB | External Database | Details |
|---|---|---|
| Gly 241 | - | expression tag |
| Ser 242 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29698.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 730.6 | |
| All* | Total formula weight | 30428.6 |
