3HAU
Crystal structure of chemically synthesized HIV-1 protease with reduced isostere MVT-101 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 protease | polymer | 99 | 10717.6 | 2 | Pfam (PF00077) UniProt (by SIFTS) (P03369) | ||
| 2 | C (A) | N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide | non-polymer | 771.0 | 1 | BIRD (PRD_000398) Chemie (2NC) | |||
| 3 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21435.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 867.0 | |
| All* | Total formula weight | 22302.2 |
