3H78

Crystal structure of Pseudomonas aeruginosa PqsD C112A mutant in complex with anthranilic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PQS biosynthetic enzyme	polymer	359	38712.2	2	UniProt (P20582) Pfam (PF08545) Pfam (PF08541)	Pseudomonas aeruginosa PAO1
2	C, D, E (A, B)	2-AMINOBENZOIC ACID	non-polymer		137.1	3	Chemie (BE2)
3	F, G (A, B)	water	water		18.0	655	Chemie (HOH)

Sequence modifications

A, B: 1 - 336 (UniProt: P20582)

PDB	External Database	Details
Gly -22	-	expression tag
Ser -21	-	expression tag
His -20	-	expression tag
Met -19	-	expression tag
Ala -18	-	expression tag
Ser -17	-	expression tag
Met -16	-	expression tag
Thr -15	-	expression tag
Gly -14	-	expression tag
Gly -13	-	expression tag
Gln -12	-	expression tag
Gln -11	-	expression tag
Met -10	-	expression tag
Gly -9	-	expression tag
Arg -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Ala 112	Cys 113	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77424.3
Non-Polymers*	Number of molecules	3
	Total formula weight	411.4
All*	Total formula weight	77835.7

*Water molecules are not included.