3H78
Crystal structure of Pseudomonas aeruginosa PqsD C112A mutant in complex with anthranilic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0030497 | biological_process | fatty acid elongation |
| A | 0033818 | molecular_function | beta-ketoacyl-acyl-carrier-protein synthase III activity |
| A | 0044550 | biological_process | secondary metabolite biosynthetic process |
| B | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0030497 | biological_process | fatty acid elongation |
| B | 0033818 | molecular_function | beta-ketoacyl-acyl-carrier-protein synthase III activity |
| B | 0044550 | biological_process | secondary metabolite biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BE2 A 350 |
| Chain | Residue |
| A | LEU81 |
| A | GLN111 |
| A | ALA112 |
| A | ASN287 |
| A | ALA289 |
| A | GLY316 |
| A | SER317 |
| A | HOH356 |
| A | HOH543 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE BE2 B 350 |
| Chain | Residue |
| B | LEU81 |
| B | GLN111 |
| B | ALA112 |
| B | LEU193 |
| B | PHE218 |
| B | HIS257 |
| B | ASN287 |
| B | GLY316 |
| B | SER317 |
| B | BE2351 |
| B | HOH425 |
| B | HOH535 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BE2 B 351 |
| Chain | Residue |
| B | MET220 |
| B | MET225 |
| B | ALA229 |
| B | HIS257 |
| B | PRO259 |
| B | ILE263 |
| B | ASN287 |
| B | BE2350 |
| B | HOH487 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Acyl-thioester intermediate","evidences":[{"source":"PubMed","id":"18728009","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19694421","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19694421","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
