3H1V
Human glucokinase in complex with a synthetic activator
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | Glucokinase | polymer | 451 | 50610.5 | 1 | UniProt (P35557) Pfam (PF00349) Pfam (PF03727) | Homo sapiens (Human) | Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D |
| 2 | B (X) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 3 | C (X) | 1-({5-[4-(methylsulfonyl)phenoxy]-2-pyridin-2-yl-1H-benzimidazol-6-yl}methyl)pyrrolidine-2,5-dione | non-polymer | 476.5 | 1 | Chemie (TK1) | |||
| 4 | D (X) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | E (X) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
X: 16 - 465 (UniProt: P35557)
| PDB | External Database | Details |
|---|---|---|
| Met 15 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50610.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 679.7 | |
| All* | Total formula weight | 51290.2 |
