3H0S
Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Acetyl-CoA carboxylase | polymer | 769 | 87238.0 | 3 | UniProt (Q00955) Pfam (PF01039) | Saccharomyces cerevisiae (yeast) | ACC, Biotin carboxylase |
| 2 | D, G, H (A, C) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E, F, I (A, B, C) | 1'-(1H-indazol-7-ylcarbonyl)-6-methylspiro[chromene-2,4'-piperidin]-4(3H)-one | non-polymer | 375.4 | 3 | Chemie (B38) | |||
| 4 | J, K, L (A, B, C) | water | water | 18.0 | 2403 | Chemie (HOH) |
Sequence modifications
A, B, C: 1476 - 2233 (UniProt: Q00955)
| PDB | External Database | Details |
|---|---|---|
| Met 1473 | - | expression tag |
| Ala 1474 | - | expression tag |
| Ser 1475 | - | expression tag |
| Leu 2234 | - | expression tag |
| Glu 2235 | - | expression tag |
| His 2236 | - | expression tag |
| His 2237 | - | expression tag |
| His 2238 | - | expression tag |
| His 2239 | - | expression tag |
| His 2240 | - | expression tag |
| His 2241 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 261713.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1414.4 | |
| All* | Total formula weight | 263128.4 |
