3H0S
Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 7
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003989 | molecular_function | acetyl-CoA carboxylase activity |
| A | 0016874 | molecular_function | ligase activity |
| B | 0003989 | molecular_function | acetyl-CoA carboxylase activity |
| B | 0016874 | molecular_function | ligase activity |
| C | 0003989 | molecular_function | acetyl-CoA carboxylase activity |
| C | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2 |
| Chain | Residue |
| A | GLY1751 |
| A | LEU1775 |
| A | GLY1779 |
| A | THR1780 |
| A | GLN1781 |
| A | HOH2316 |
| A | HOH2498 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE B38 A 101 |
| Chain | Residue |
| A | THR1757 |
| A | ALA1761 |
| A | MET1765 |
| A | VAL1923 |
| A | ARG1954 |
| A | PHE1956 |
| A | GLY1958 |
| A | LEU2025 |
| A | GLU2026 |
| A | GLN2028 |
| A | GLY2029 |
| A | HOH381 |
| A | HOH453 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE B38 B 102 |
| Chain | Residue |
| B | HOH331 |
| B | HOH796 |
| B | VAL1923 |
| B | ARG1954 |
| B | PHE1956 |
| B | GLY1958 |
| B | ARG1996 |
| B | VAL2024 |
| B | LEU2025 |
| B | GLU2026 |
| B | GLN2028 |
| B | GLY2029 |
| C | THR1757 |
| C | ALA1761 |
| C | LYS1764 |
| C | HOH2297 |
| C | HOH2310 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1 |
| Chain | Residue |
| C | ARG2154 |
| C | TRP2158 |
| C | LYS2185 |
| C | LEU2189 |
| C | HOH2389 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 3 |
| Chain | Residue |
| C | HOH455 |
| C | GLY1751 |
| C | LEU1775 |
| C | GLY1779 |
| C | THR1780 |
| C | GLN1781 |
| C | HOH2345 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE B38 C 100 |
| Chain | Residue |
| B | ALA1761 |
| B | MET1765 |
| C | HOH560 |
| C | VAL1923 |
| C | ARG1954 |
| C | PHE1956 |
| C | GLY1958 |
| C | LEU2025 |
| C | GLU2026 |
| C | GLY2029 |
| C | HOH2475 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 672 |
| Details | Domain: {"description":"CoA carboxyltransferase N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01136","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12663926","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"26458104","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1OD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CSL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12663926","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1OD2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26458104","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5CSL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
