3GZ3

Leishmania major Dihydroorotate Dehydrogenase in complex with orotate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Dihydroorotate dehydrogenase, putative	polymer	354	38159.5	2	UniProt (Q4QEW7) Pfam (PF01180) In PDB	Leishmania major
2	A, B	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	2	Chemie (FMN)
3	A, B	OROTIC ACID	non-polymer		156.1	2	Chemie (ORO)
4	A, B	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
5		water	water		18.0	430	Chemie (HOH)

Sequence modifications

A, B: 1 - 320 (UniProt: Q4QEW7)

PDB	External Database	Details
Met -33	-	expression tag
Gly -32	-	expression tag
Ser -31	-	expression tag
Ser -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Leu -20	-	expression tag
Val -19	-	expression tag
Pro -18	-	expression tag
Ala -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag
Ala -12	-	expression tag
Ser -11	-	expression tag
Met -10	-	expression tag
Thr -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gln -6	-	expression tag
Gln -5	-	expression tag
Met -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76319.1
Non-Polymers*	Number of molecules	8
	Total formula weight	1593.3
All*	Total formula weight	77912.3

*Water molecules are not included.