3GQF
Structural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Superoxide dismutase [Cu-Zn] | polymer | 153 | 15836.6 | 6 | UniProt (P00441) Pfam (PF00080) | Homo sapiens (Human) | |
| 2 | G, I, K, M, O... (A, B, C, D, E...) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | H, J, L, N, Q (A, B, C, D, F) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 4 | R, S, T, U, V... (A, B, C, D, E...) | water | water | 18.0 | 498 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 153 (UniProt: P00441)
| PDB | External Database | Details |
|---|---|---|
| Arg 46 | His 47 | engineered mutation |
| Gln 48 | His 49 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 95019.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 592.8 | |
| All* | Total formula weight | 95612.4 |
