3GOP
Crystal structure of the EGF receptor juxtamembrane and kinase domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 361 | 41667.3 | 1 | UniProt (P00533) Pfam (PF21314) Pfam (PF07714) | Homo sapiens (human) | Receptor tyrosine-protein kinase ErbB-1 |
| 2 | B (A) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A: 645 - 998 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Met 638 | - | expression tag |
| His 639 | - | expression tag |
| His 640 | - | expression tag |
| His 641 | - | expression tag |
| His 642 | - | expression tag |
| His 643 | - | expression tag |
| His 644 | - | expression tag |
| Met 721 | Lys 745 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41667.3 | |
| All* | Total formula weight | 41667.3 |
