3GOP

Crystal structure of the EGF receptor juxtamembrane and kinase domains

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Epidermal growth factor receptor	polymer	361	41667.3	1	UniProt (P00533) Pfam (PF21314) Pfam (PF07714) In PDB	Homo sapiens (human)	Receptor tyrosine-protein kinase ErbB-1
2		water	water		18.0	5	Chemie (HOH)

Sequence modifications

A: 645 - 998 (UniProt: P00533)

PDB	External Database	Details
Met 638	-	expression tag
His 639	-	expression tag
His 640	-	expression tag
His 641	-	expression tag
His 642	-	expression tag
His 643	-	expression tag
His 644	-	expression tag
Met 721	Lys 745	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41667.3
All*	Total formula weight	41667.3

*Water molecules are not included.