3GID

The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2) in complex with Soraphen A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Acetyl-CoA carboxylase 2	polymer	540	60092.9	2	UniProt (O00763) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785)	Homo sapiens (human)	ACC-beta, Biotin carboxylase
2	C, D (A, B)	SORAPHEN A	non-polymer		520.7	2	Chemie (S1A)
3	E, F (A, B)	water	water		18.0	197	Chemie (HOH)

Sequence modifications

A, B: 238 - 760 (UniProt: O00763)

PDB	External Database	Details
Met 221	-	expression tag
Gly 222	-	expression tag
Ser 223	-	expression tag
Ser 224	-	expression tag
His 225	-	expression tag
His 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag
Glu 231	-	expression tag
Asn 232	-	expression tag
Leu 233	-	expression tag
Tyr 234	-	expression tag
Phe 235	-	expression tag
Gln 236	-	expression tag
Gly 237	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	120185.9
Non-Polymers*	Number of molecules	2
	Total formula weight	1041.3
All*	Total formula weight	121227.2

*Water molecules are not included.