3GID
The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2) in complex with Soraphen A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetyl-CoA carboxylase 2 | polymer | 540 | 60092.9 | 2 | UniProt (O00763) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785) | Homo sapiens (human) | ACC-beta, Biotin carboxylase |
| 2 | C, D (A, B) | SORAPHEN A | non-polymer | 520.7 | 2 | Chemie (S1A) PubChem (19760708) PubChem (22524564) PubChem (177587178) PubChem (46936509) PubChem (58092550) PubChem (89433009) PubChem (5281897) PubChem (129738) PubChem (4488322) PubChem (6439124) PubChem (10098191) PubChem (118084081) PubChem (11953950) PubChem (12041542) PubChem (137628570) PubChem (154497487) PubChem (133634301) PubChem (134815582) PubChem (143762910) PubChem (156580543) PubChem (161569847) PubChem (161569848) PubChem (162922319) PubChem (164674813) PubChem (169543746) PubChem (172653356) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A, B: 238 - 760 (UniProt: O00763)
| PDB | External Database | Details |
|---|---|---|
| Met 221 | - | expression tag |
| Gly 222 | - | expression tag |
| Ser 223 | - | expression tag |
| Ser 224 | - | expression tag |
| His 225 | - | expression tag |
| His 226 | - | expression tag |
| His 227 | - | expression tag |
| His 228 | - | expression tag |
| His 229 | - | expression tag |
| His 230 | - | expression tag |
| Glu 231 | - | expression tag |
| Asn 232 | - | expression tag |
| Leu 233 | - | expression tag |
| Tyr 234 | - | expression tag |
| Phe 235 | - | expression tag |
| Gln 236 | - | expression tag |
| Gly 237 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120185.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1041.3 | |
| All* | Total formula weight | 121227.2 |
