3GHG

Crystal Structure of Human Fibrinogen

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J (A, D, G, J)	Fibrinogen alpha chain	polymer	562	60969.8	4	UniProt (P02671) Pfam (PF08702) Pfam (PF12160)	Homo sapiens (human)
2	B, E, H, K (B, E, H, K)	Fibrinogen beta chain	polymer	461	52379.4	4	UniProt (P02675) Pfam (PF08702) Pfam (PF00147)	Homo sapiens (human)
3	C, F, I, L (C, F, I, L)	Fibrinogen gamma chain	polymer	411	46521.8	4	UniProt (P02679) Pfam (PF08702) Pfam (PF00147)	Homo sapiens (human)
4	M, N, Q, R (M, N, Q, R)	A knob	polymer	4	426.5	4
5	O, P, S, T (O, P, S, T)	B knob	polymer	4	467.5	4
6	U, V, X (U, V, X)	N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		2224.0	3	In PDB GlyTouCan (G84467IZ)
7	W (W)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
8	Y (Y)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
9	AA, BA, CA, DA, EA... (C, E, F, H, I...)	CALCIUM ION	non-polymer		40.1	8	Chemie (CA)

Contents of the asymmetric unit

Polymers	Number of chains	20
	Total formula weight	643059.9
Branched	Number of molecules	5
	Total formula weight	8007.2
Non-Polymers*	Number of molecules	8
	Total formula weight	320.6
All*	Total formula weight	651387.8

*Water molecules are not included.