3GEY
Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment in complex with an inhibitor Pj34
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Poly [ADP-ribose] polymerase 15 | polymer | 221 | 25439.5 | 4 | UniProt (Q460N3) Pfam (PF00644) In PDB | Homo sapiens (Human) | PARP-15, B-aggressive lymphoma protein 3 |
2 | A, B | N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE | non-polymer | 295.3 | 2 | Chemie (P34) | |||
3 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 459 - 656 (UniProt: Q460N3)
PDB | External Database | Details |
---|---|---|
Met 436 | - | expression tag |
His 437 | - | expression tag |
His 438 | - | expression tag |
His 439 | - | expression tag |
His 440 | - | expression tag |
His 441 | - | expression tag |
His 442 | - | expression tag |
Ser 443 | - | expression tag |
Ser 444 | - | expression tag |
Gly 445 | - | expression tag |
Val 446 | - | expression tag |
Asp 447 | - | expression tag |
Leu 448 | - | expression tag |
Gly 449 | - | expression tag |
Thr 450 | - | expression tag |
Glu 451 | - | expression tag |
Asn 452 | - | expression tag |
Leu 453 | - | expression tag |
Tyr 454 | - | expression tag |
Phe 455 | - | expression tag |
Gln 456 | - | expression tag |
Ser 457 | - | expression tag |
Met 458 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 101757.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 590.7 | |
All* | Total formula weight | 102348.5 |