3GCW
PCSK9:EGFA(H306Y)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | P | Proprotein convertase subtilisin/kexin type 9 | polymer | 100 | 11283.9 | 1 | UniProt (Q8NBP7) Pfam (PF05922) In PDB | Homo sapiens (human) | Proprotein convertase PC9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1, NARC-1 |
| 2 | A | Proprotein convertase subtilisin/kexin type 9 | polymer | 540 | 57443.7 | 1 | UniProt (Q8NBP7) Pfam (PF00082) Pfam (PF18459) Pfam (PF18464) Pfam (PF18463) In PDB | Homo sapiens (human) | Proprotein convertase PC9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1, NARC-1 |
| 3 | E | Low-density lipoprotein receptor | polymer | 83 | 9115.2 | 1 | UniProt (P01130) In PDB | Homo sapiens (human) | LDL receptor |
| 4 | E | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
E: 293 - 372 (UniProt: P01130)
| PDB | External Database | Details |
|---|---|---|
| Gly 290 | - | expression tag |
| Ala 291 | - | expression tag |
| Met 292 | - | expression tag |
| Tyr 306 | His 327 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 77842.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 77882.9 |
