3GBN
Crystal Structure of Fab CR6261 in Complex with the 1918 H1N1 influenza virus hemagglutinin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemagglutinin | polymer | 331 | 36452.8 | 1 | UniProt (Q9WFX3) Pfam (PF00509) | Influenza A virus (A/Brevig Mission/1/1918(H1N1)) (Influenza A virus (strain A/South Carolina/1/1918 H1N1)) | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain |
| 2 | B (B) | Hemagglutinin | polymer | 179 | 20394.4 | 1 | UniProt (Q9WFX3) Pfam (PF00509) | Influenza A virus (A/Brevig Mission/1/1918(H1N1)) (Influenza A virus (strain A/South Carolina/1/1918 H1N1)) | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain |
| 3 | C (H) | Fab Heavy Chain | polymer | 226 | 23981.1 | 1 | Homo sapiens | ||
| 4 | D (L) | Fab Lambda Light Chain | polymer | 221 | 23257.8 | 1 | Homo sapiens | ||
| 5 | E (C) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 6 | F, J (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | G, M, N, O, Q (A, B, H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 8 | H, K (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | I (A) | 2-ETHOXYETHANOL | non-polymer | 90.1 | 1 | Chemie (ETX) | |||
| 10 | L (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 11 | P (B) | UNKNOWN LIGAND | non-polymer | 1 | Chemie (UNL) | ||||
| 12 | R, S, T, U (A, B, H, L) | water | water | 18.0 | 293 | Chemie (HOH) |
Sequence modifications
A: 11 - 329 (UniProt: Q9WFX3)
B: 1 - 176 (UniProt: Q9WFX3)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 177 | - | expression tag |
| Gly 178 | - | expression tag |
| Arg 179 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 104086.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1062.5 | |
| All* | Total formula weight | 105897.4 |
