3GBM

Crystal Structure of Fab CR6261 in Complex with a H5N1 influenza virus hemagglutinin.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Hemagglutinin	polymer	334	37948.0	2	UniProt (Q6DQ33) Pfam (PF00509)	Influenza A virus (A/Viet Nam/1203/2004(H5N1)) (A/Viet Nam/1203/2004(H5N1))
2	B, D (B, D)	Hemagglutinin	polymer	177	20414.5	2	UniProt (Q6DQ33) Pfam (PF00509)	Influenza A virus (A/Viet Nam/1203/2004(H5N1)) (A/Viet Nam/1203/2004(H5N1))
3	E, G (H, I)	antibody (Fab)	polymer	226	23981.1	2		Homo sapiens
4	F, H (L, M)	antibody (Fab)	polymer	221	23257.8	2		Homo sapiens
5	I, J (E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
6	K, M, O, R, T (A, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
7	L, Q (A, C)	beta-D-mannopyranose	non-polymer		180.2	2	Chemie (BMA)
8	N, S (A, C)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
9	P (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
10	AA, BA, U, V, W... (I, M, A, B, C...)	water	water		18.0	164	Chemie (HOH)

Sequence modifications

A, C: 11 - 333 (UniProt: Q6DQ33)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag

B, D: 1 - 174 (UniProt: Q6DQ33)

PDB	External Database	Details
Ser 175	-	expression tag
Gly 176	-	expression tag
Arg 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	211202.9
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	10
	Total formula weight	1682.6
All*	Total formula weight	213734.3

*Water molecules are not included.