3G8I
Aleglitazar, a new, potent, and balanced PPAR alpha/gamma agonist for the treatment of type II diabetes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor alpha | polymer | 270 | 30571.7 | 1 | UniProt (Q07869) Pfam (PF00104) | Homo sapiens (Human) | PPAR-alpha, Nuclear receptor subfamily 1 group C member 1 |
| 2 | B (Z) | Nuclear receptor coactivator 1 | polymer | 13 | 1660.9 | 1 | UniProt (Q15788) | Coactivator peptide SRC-1, NCoA-1, Steroid receptor coactivator 1, SRC-1, RIP160, Protein Hin-2, Renal carcinoma antigen NY-REN-52 | |
| 3 | C (A) | (2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid | non-polymer | 437.5 | 1 | Chemie (RO7) | |||
| 4 | D, E (A, Z) | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32232.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 437.5 | |
| All* | Total formula weight | 32670.1 |
