3G5O

The crystal structure of the toxin-antitoxin complex RelBE2 (Rv2865-2866) from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Uncharacterized protein Rv2865	polymer	108	11859.1	2	UniProt (O33347) Pfam (PF02604)	Mycobacterium tuberculosis
2	B, C (B, C)	Uncharacterized protein Rv2866	polymer	102	12076.9	2	UniProt (O33348) Pfam (PF05016)	Mycobacterium tuberculosis
3	E (A)	THIOCYANATE ION	non-polymer		58.1	1	Chemie (SCN)
4	F (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	G (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6	H (A)	IMIDAZOLE	non-polymer		69.1	1	Chemie (IMD)
7	I (C)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
8	J, K, L, M (A, B, C, D)	water	water		18.0	173	Chemie (HOH)

Sequence modifications

A, D: 8 - 100 (UniProt: O33347)

PDB	External Database	Details
Met 1	-	expression tag
Gln 2	-	expression tag
Ala 3	-	expression tag
Gly 4	-	expression tag
Pro 5	-	expression tag
Ala 6	-	expression tag
Leu 7	-	expression tag
Asp 101	-	expression tag
Tyr 102	-	expression tag
Lys 103	-	expression tag
Asp 104	-	expression tag
Asp 105	-	expression tag
Asp 106	-	expression tag
Asp 107	-	expression tag
Lys 108	-	expression tag

B, C: 15 - 102 (UniProt: O33348)

PDB	External Database	Details
Met 1	-	expression tag
Ala 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Val 9	-	expression tag
Asp 10	-	expression tag
Asp 11	-	expression tag
Asp 12	-	expression tag
Asp 13	-	expression tag
Lys 14	-	expression tag
Val 16	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	47872.0
Non-Polymers*	Number of molecules	5
	Total formula weight	376.9
All*	Total formula weight	48248.8

*Water molecules are not included.