3G5O

The crystal structure of the toxin-antitoxin complex RelBE2 (Rv2865-2866) from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005515	molecular_function	protein binding
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0043565	molecular_function	sequence-specific DNA binding
A	0045927	biological_process	positive regulation of growth
A	0097351	molecular_function	toxin sequestering activity
B	0003677	molecular_function	DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0006351	biological_process	DNA-templated transcription
B	0006401	biological_process	RNA catabolic process
B	0006402	biological_process	mRNA catabolic process
B	0016787	molecular_function	hydrolase activity
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045926	biological_process	negative regulation of growth
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0006351	biological_process	DNA-templated transcription
C	0006401	biological_process	RNA catabolic process
C	0006402	biological_process	mRNA catabolic process
C	0016787	molecular_function	hydrolase activity
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0045926	biological_process	negative regulation of growth
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0005515	molecular_function	protein binding
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
D	0043565	molecular_function	sequence-specific DNA binding
D	0045927	biological_process	positive regulation of growth
D	0097351	molecular_function	toxin sequestering activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SCN A 503

Chain	Residue
A	ILE78
A	THR83
A	GOL504

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 501

Chain	Residue
A	TYR60
B	ARG76

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
C	HOH111
A	ILE78
A	ALA79
A	SCN503
C	ARG36

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IMD A 505

Chain	Residue
A	ILE78
B	ARG80
B	ASP82
B	VAL89

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site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE TRS C 502

Chain	Residue
C	VAL56
C	LYS58
C	SER69
C	ALA70
C	ARG71
C	HOH106
C	HOH124
D	GLU53

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