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3G5O

The crystal structure of the toxin-antitoxin complex RelBE2 (Rv2865-2866) from Mycobacterium tuberculosis

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0005515molecular_functionprotein binding
A0006355biological_processregulation of DNA-templated transcription
A0045927biological_processpositive regulation of growth
A0097351molecular_functiontoxin sequestering activity
B0003677molecular_functionDNA binding
B0004518molecular_functionnuclease activity
B0004519molecular_functionendonuclease activity
B0005515molecular_functionprotein binding
B0006401biological_processRNA catabolic process
B0045892biological_processnegative regulation of DNA-templated transcription
B0045926biological_processnegative regulation of growth
C0003677molecular_functionDNA binding
C0004518molecular_functionnuclease activity
C0004519molecular_functionendonuclease activity
C0005515molecular_functionprotein binding
C0006401biological_processRNA catabolic process
C0045892biological_processnegative regulation of DNA-templated transcription
C0045926biological_processnegative regulation of growth
D0003677molecular_functionDNA binding
D0005515molecular_functionprotein binding
D0006355biological_processregulation of DNA-templated transcription
D0045927biological_processpositive regulation of growth
D0097351molecular_functiontoxin sequestering activity
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SCN A 503
ChainResidue
AILE78
ATHR83
AGOL504

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CL A 501
ChainResidue
ATYR60
BARG76

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL A 504
ChainResidue
CHOH111
AILE78
AALA79
ASCN503
CARG36

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE IMD A 505
ChainResidue
AILE78
BARG80
BASP82
BVAL89

site_idAC5
Number of Residues8
DetailsBINDING SITE FOR RESIDUE TRS C 502
ChainResidue
CVAL56
CLYS58
CSER69
CALA70
CARG71
CHOH106
CHOH124
DGLU53

227111

PDB entries from 2024-11-06

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