3G5C

Structural and biochemical studies on the ectodomain of human ADAM22

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	ADAM 22	polymer	510	56245.7	2	UniProt (Q9P0K1) Pfam (PF01421) Pfam (PF00200) Pfam (PF08516) Pfam (PF07974) In PDB	Homo sapiens (Human)	A disintegrin and metalloproteinase domain 22, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2, Metalloproteinase-disintegrin ADAM22-3
2	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
3	A, B	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)
4		water	water		18.0	369	Chemie (HOH)

Sequence modifications

A, B: 233 - 736 (UniProt: Q9P0K1)

PDB	External Database	Details
His 737	-	expression tag
His 738	-	expression tag
His 739	-	expression tag
His 740	-	expression tag
His 741	-	expression tag
His 742	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	112491.4
Non-Polymers*	Number of molecules	12
	Total formula weight	1567.7
All*	Total formula weight	114059.1

*Water molecules are not included.