3G45
Crystal structure of human phosphodiesterase 4b with regulatory domain and d155988
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | polymer | 421 | 48442.7 | 2 | UniProt (Q07343) Pfam (PF18100) Pfam (PF00233) In PDB | Homo sapiens (human) | DPDE4, PDE32 |
2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A, B | 8-(3-nitrophenyl)-6-(pyridin-4-ylmethyl)quinoline | non-polymer | 341.4 | 2 | Chemie (988) | |||
5 | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A, B: 241 - 294 (UniProt: Q07343)
A, B: 305 - 659 (UniProt: Q07343)
PDB | External Database | Details |
---|---|---|
Met 240 | - | expression tag |
His 660 | - | expression tag |
His 661 | - | expression tag |
His 662 | - | expression tag |
His 663 | - | expression tag |
His 664 | - | expression tag |
His 665 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Lys 295 | - | linker |
Val 296 | - | linker |
Thr 297 | - | linker |
Ala 298 | - | linker |
Glu 299 | - | linker |
Glu 300 | - | linker |
Ala 301 | - | linker |
Pro 302 | - | linker |
Gln 303 | - | linker |
Pro 304 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 96885.4 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 862.2 | |
All* | Total formula weight | 97747.6 |