3G43
Crystal structure of the calmodulin-bound Cav1.2 C-terminal regulatory domain dimer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Calmodulin | polymer | 148 | 16721.3 | 4 | UniProt (P62158) Pfam (PF13499) UniProt (by SIFTS) (P0DP23) In PDB | Homo sapiens (Human) | CaM |
2 | E, F | Voltage-dependent L-type calcium channel subunit alpha-1C | polymer | 81 | 9356.9 | 2 | UniProt (Q13936) Pfam (PF08763) In PDB | Homo sapiens (Human) | Voltage-gated calcium channel subunit alpha Cav1.2, Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle |
3 | A, B, C, D | CALCIUM ION | non-polymer | 40.1 | 14 | Chemie (CA) | |||
4 | water | water | 18.0 | 518 | Chemie (HOH) |
Sequence modifications
E, F: 1609 - 1682 (UniProt: Q13936)
PDB | External Database | Details |
---|---|---|
Gly 1604 | - | expression tag |
Pro 1605 | - | expression tag |
Leu 1606 | - | expression tag |
Gly 1607 | - | expression tag |
Ser 1608 | - | expression tag |
Glu 1683 | - | expression tag |
Gln 1684 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 85599.2 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 561.1 | |
All* | Total formula weight | 86160.3 |