3G43
Crystal structure of the calmodulin-bound Cav1.2 C-terminal regulatory domain dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Calmodulin | polymer | 148 | 16721.3 | 4 | UniProt (P62158) Pfam (PF13499) UniProt (by SIFTS) (P0DP23) | Homo sapiens (Human) | CaM |
| 2 | E, F (E, F) | Voltage-dependent L-type calcium channel subunit alpha-1C | polymer | 81 | 9356.9 | 2 | UniProt (Q13936) Pfam (PF08763) | Homo sapiens (Human) | Voltage-gated calcium channel subunit alpha Cav1.2, Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle |
| 3 | G, H, I, J, K... (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 14 | Chemie (CA) | |||
| 4 | U, V, W, X, Y... (A, B, C, D, E...) | water | water | 18.0 | 518 | Chemie (HOH) |
Sequence modifications
E, F: 1609 - 1682 (UniProt: Q13936)
| PDB | External Database | Details |
|---|---|---|
| Gly 1604 | - | expression tag |
| Pro 1605 | - | expression tag |
| Leu 1606 | - | expression tag |
| Gly 1607 | - | expression tag |
| Ser 1608 | - | expression tag |
| Glu 1683 | - | expression tag |
| Gln 1684 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 85599.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 561.1 | |
| All* | Total formula weight | 86160.3 |
