3G2G
S437Y Mutant of human muscle pyruvate kinase, isoform M2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate kinase isozymes M1/M2 | polymer | 533 | 58237.1 | 4 | UniProt (P14618) Pfam (PF00224) Pfam (PF02887) | Homo sapiens (Human) | Pyruvate kinase muscle isozyme, Pyruvate kinase 2/3, Cytosolic thyroid hormone-binding protein, CTHBP, THBP1 |
| 2 | AA, BA, CA, E, F... (C, A, B, D) | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 3 | DA, EA, FA, G, GA... (C, A, B, D) | UNKNOWN ATOM OR ION | non-polymer | 31 | Chemie (UNX) | ||||
| 4 | WA, XA, YA, ZA (A, B, C, D) | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 531 (UniProt: P14618)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Tyr 437 | Ser 437 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 232948.3 | |
| Non-Polymers* | Number of molecules | 44 |
| Total formula weight | 1248.8 | |
| All* | Total formula weight | 234197.2 |
