3G2G
S437Y Mutant of human muscle pyruvate kinase, isoform M2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Pyruvate kinase isozymes M1/M2 | polymer | 533 | 58237.1 | 4 | UniProt (P14618) Pfam (PF00224) Pfam (PF02887) In PDB | Homo sapiens (Human) | Pyruvate kinase muscle isozyme, Pyruvate kinase 2/3, Cytosolic thyroid hormone-binding protein, CTHBP, THBP1 |
2 | C, A, B, D | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
3 | C, A, B, D | UNKNOWN ATOM OR ION | non-polymer | 31 | Chemie (UNX) | ||||
4 | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 531 (UniProt: P14618)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Tyr 437 | Ser 437 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 232948.3 | |
Non-Polymers* | Number of molecules | 44 |
Total formula weight | 1248.8 | |
All* | Total formula weight | 234197.2 |