3G2F

Crystal structure of the kinase domain of bone morphogenetic protein receptor type II (BMPR2) at 2.35 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Bone morphogenetic protein receptor type-2	polymer	336	38775.5	2	UniProt (Q13873) Pfam (PF00069)	Homo sapiens (Human)	Bone morphogenetic protein receptor type II, BMP type II receptor, BMPR-II
2	C, I (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
3	D, J (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	E, K (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	F, G, H, L (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
6	M, N (A, B)	water	water		18.0	122	Chemie (HOH)

Sequence modifications

A, B: 189 - 517 (UniProt: Q13873)

PDB	External Database	Details
Ala 518	-	expression tag
His 519	-	expression tag
His 520	-	expression tag
His 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77551.1
Non-Polymers*	Number of molecules	10
	Total formula weight	1343.4
All*	Total formula weight	78894.5

*Water molecules are not included.