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3G1V

Crystal structure of the mutant D70G of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5-fluorouridine 5'-monophosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Orotidine 5'-phosphate decarboxylasepolymer22824826.72UniProt (O26232)
Pfam (PF00215)
Methanothermobacter thermautotrophicus str. Delta HOMP decarboxylase, OMPDCase, OMPdecase
2C, E
(A, B)
5-FLUORO-URIDINE-5'-MONOPHOSPHATEnon-polymer342.22Chemie (5FU)
3D, F
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4G, H
(A, B)
waterwater18.0281Chemie (HOH)
Sequence modifications
A, B: 1 - 228 (UniProt: O26232)
PDBExternal DatabaseDetails
Gly 70Asp 70engineered mutation
Pro 101Arg 101engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight49653.3
Non-Polymers*Number of molecules4
Total formula weight755.3
All*Total formula weight50408.6
*Water molecules are not included.

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PDB entries from 2025-07-02

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