3G1V
Crystal structure of the mutant D70G of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5-fluorouridine 5'-monophosphate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Orotidine 5'-phosphate decarboxylase | polymer | 228 | 24826.7 | 2 | UniProt (O26232) Pfam (PF00215) In PDB | Methanothermobacter thermautotrophicus str. Delta H | OMP decarboxylase, OMPDCase, OMPdecase |
2 | A, B | 5-FLUORO-URIDINE-5'-MONOPHOSPHATE | non-polymer | 342.2 | 2 | Chemie (5FU) | |||
3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
4 | water | water | 18.0 | 281 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 228 (UniProt: O26232)
PDB | External Database | Details |
---|---|---|
Gly 70 | Asp 70 | engineered mutation |
Pro 101 | Arg 101 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 49653.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 755.3 | |
All* | Total formula weight | 50408.6 |