3G15
Crystal structure of human choline kinase alpha in complex with hemicholinium-3 and ADP
Replaces: 3F2SEntity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Choline kinase alpha | polymer | 401 | 46856.5 | 2 | UniProt (P35790) Pfam (PF01633) In PDB | Homo sapiens (human) | CK, CHETK-alpha |
2 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
4 | A, B | (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium) | non-polymer | 414.5 | 2 | Chemie (HC6) | |||
5 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
6 | B, A | UNKNOWN ATOM OR ION | non-polymer | 21 | Chemie (UNX) | ||||
7 | water | water | 18.0 | 324 | Chemie (HOH) |
Sequence modifications
A, B: 75 - 457 (UniProt: P35790)
PDB | External Database | Details |
---|---|---|
Gly 57 | - | expression tag |
Ser 58 | - | expression tag |
Ser 59 | - | expression tag |
His 60 | - | expression tag |
His 61 | - | expression tag |
His 62 | - | expression tag |
His 63 | - | expression tag |
His 64 | - | expression tag |
His 65 | - | expression tag |
Ser 66 | - | expression tag |
Ser 67 | - | expression tag |
Gly 68 | - | expression tag |
Leu 69 | - | expression tag |
Val 70 | - | expression tag |
Pro 71 | - | expression tag |
Arg 72 | - | expression tag |
Gly 73 | - | expression tag |
Ser 74 | - | expression tag |
Met 154 | Val 154 | variant |
Ser 220 | Gly 220 | variant |
Leu 422 | Gln 422 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 93713.0 | |
Non-Polymers* | Number of molecules | 31 |
Total formula weight | 1972.8 | |
All* | Total formula weight | 95685.8 |