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3G0X

Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 5

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADihydroorotate dehydrogenasepolymer36739856.51UniProt (Q02127)
Pfam (PF01180)
In PDB
Homo sapiens (human)DHOdehase, Dihydroorotate oxidase
2AFLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
3AOROTIC ACIDnon-polymer156.11Chemie (ORO)
4A(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamidenon-polymer304.31Chemie (MD7)
5ASULFATE IONnon-polymer96.11Chemie (SO4)
6waterwater18.0239Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39856.5
Non-Polymers*Number of molecules4
Total formula weight1012.8
All*Total formula weight40869.4
*Water molecules are not included.

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PDB entries from 2024-07-17

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