3FZY

Crystal Structure of Pre-cleavage Form of Cysteine Protease Domain from Vibrio cholerae RtxA Toxin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	RTX toxin RtxA	polymer	234	25551.0	2	UniProt (Q9KS12) Pfam (PF11713)	Vibrio cholerae
2	C, Q (A, B)	INOSITOL HEXAKISPHOSPHATE	non-polymer		660.0	2	Chemie (IHP)
3	D (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	E, F, G, H, I... (A)	UNKNOWN ATOM OR ION	non-polymer			12	Chemie (UNX)
5	R, S (A, B)	water	water		18.0	313	Chemie (HOH)

Sequence modifications

A, B: 0 - 3637 (UniProt: Q9KS12)

PDB	External Database	Details
Met -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ser 3568	Cys 3581	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51101.9
Non-Polymers*	Number of molecules	15
	Total formula weight	1355.5
All*	Total formula weight	52457.4

*Water molecules are not included.