3FZT
Crystal structure of PYK2 complexed with PF-4618433
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein tyrosine kinase 2 beta | polymer | 277 | 32190.3 | 1 | UniProt (Q14289) Pfam (PF07714) | Homo sapiens (Human) | Focal adhesion kinase 2, FADK 2, Proline-rich tyrosine kinase 2, Cell adhesion kinase beta, CAK beta, Calcium-dependent tyrosine kinase, CADTK, Related adhesion focal tyrosine kinase, RAFTK |
| 2 | B (A) | 1-[5-tert-butyl-2-(4-methylphenyl)-1,2-dihydro-3H-pyrazol-3-ylidene]-3-{3-[(pyridin-3-yloxy)methyl]-1H-pyrazol-5-yl}urea | non-polymer | 445.5 | 1 | Chemie (4JZ) | |||
| 3 | C (A) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32190.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 445.5 | |
| All* | Total formula weight | 32635.8 |
