Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE 4JZ A 999 |
Chain | Residue |
A | LYS457 |
A | LEU556 |
A | LEU565 |
A | GLY566 |
A | ASP567 |
A | PHE568 |
A | ARG572 |
A | HOH1011 |
A | HOH1033 |
A | SER473 |
A | GLU474 |
A | MET478 |
A | VAL487 |
A | MET502 |
A | GLU503 |
A | LEU504 |
A | TYR505 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 27 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGFFGEVYeGvytnhkgekin.......VAVK |
Chain | Residue | Details |
A | LEU431-LYS457 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CVHrDIAVRNILV |
Chain | Residue | Details |
A | CYS545-VAL557 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP549 | |
Chain | Residue | Details |
A | LEU431 | |
A | LYS457 | |
A | GLU503 | |
Chain | Residue | Details |
A | TYR579 | |
Chain | Residue | Details |
A | TYR580 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ARG553 | |
A | ASP549 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ALA551 | |
A | ASP549 | |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASN554 | |
A | ALA551 | |
A | ASP549 | |