3FXX
Human EphA3 Kinase and Juxtamembrane Region Bound to Substrate KQWDNYE[pTyr]IW
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ephrin type-A receptor 3 | polymer | 371 | 41819.7 | 1 | UniProt (P29320) Pfam (PF14575) Pfam (PF07714) Pfam (PF07647) | Homo sapiens (Human) | Tyrosine-protein kinase receptor ETK1, HEK, HEK4, Tyrosine-protein kinase TYRO4 |
| 2 | B (B) | peptide substrate | polymer | 10 | 1525.5 | 1 | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 301 | Chemie (HOH) |
Sequence modifications
A: 577 - 947 (UniProt: P29320)
| PDB | External Database | Details |
|---|---|---|
| Thr 608 | Ala 608 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43345.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 530.5 | |
| All* | Total formula weight | 43875.8 |
