3FW3
Crystal Structure of soluble domain of CA4 in complex with Dorzolamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Carbonic anhydrase 4 | polymer | 266 | 30364.5 | 2 | UniProt (P22748) Pfam (PF00194) | Homo sapiens (Human) | Carbonic anhydrase IV, CA-IV, Carbonate dehydratase IV |
2 | C, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | D, H (A, B) | (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE | non-polymer | 324.4 | 2 | Chemie (ETS) | |||
4 | E (A) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
5 | F, I (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
6 | J, K (A, B) | water | water | 18.0 | 264 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 60728.9 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1152.0 | |
All* | Total formula weight | 61880.9 |