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3FW3

Crystal Structure of soluble domain of CA4 in complex with Dorzolamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Carbonic anhydrase 4polymer26630364.52UniProt (P22748)
Pfam (PF00194)
Homo sapiens (Human)Carbonic anhydrase IV, CA-IV, Carbonate dehydratase IV
2C, G
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, H
(A, B)
(4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDEnon-polymer324.42Chemie (ETS)
4E
(A)
alpha-D-glucopyranosenon-polymer180.21Chemie (GLC)
5F, I
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
6J, K
(A, B)
waterwater18.0264Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight60728.9
Non-Polymers*Number of molecules7
Total formula weight1152.0
All*Total formula weight61880.9
*Water molecules are not included.

227344

PDB entries from 2024-11-13

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