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3FW0

Structure of Peptidyl-alpha-hydroxyglycine alpha-Amidating Lyase (PAL) bound to alpha-hydroxyhippuric acid (non-peptidic substrate)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Peptidyl-glycine alpha-amidating monooxygenasepolymer32936914.11UniProt (P14925)
Pfam (PF01436)
Rattus norvegicus (brown rat rat rats)PAM, Peptidylglycine alpha-hydroxylating monooxygenase, PHM, Peptidyl-alpha-hydroxyglycine alpha-amidating lyase, Peptidylamidoglycolate lyase, PAL
2B, C
(A)
MERCURY (II) IONnon-polymer200.62Chemie (HG)
3D
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
4E
(A)
(2S)-hydroxy[(phenylcarbonyl)amino]ethanoic acidnon-polymer195.21Chemie (HH3)
5F
(A)
waterwater18.0118Chemie (HOH)
Sequence modifications
A: 498 - 820 (UniProt: P14925)
PDBExternal DatabaseDetails
His 492-expression tag
His 493-expression tag
His 494-expression tag
His 495-expression tag
His 496-expression tag
His 497-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight36914.1
Non-Polymers*Number of molecules4
Total formula weight636.4
All*Total formula weight37550.5
*Water molecules are not included.

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PDB entries from 2025-07-30

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