3FUR
Crystal Structure of PPARg in complex with INT131
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 272 | 31094.1 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma, Nuclear receptor subfamily 1 group C member 3 |
| 2 | B (H) | Nuclear receptor coactivator 1 | polymer | 12 | 1343.6 | 1 | UniProt (Q15788) | synthetic construct | NCoA-1, Steroid receptor coactivator 1, SRC-1, RIP160, Protein Hin-2, Renal carcinoma antigen NY-REN-52 |
| 3 | C (A) | 2,4-dichloro-N-[3,5-dichloro-4-(quinolin-3-yloxy)phenyl]benzenesulfonamide | non-polymer | 514.2 | 1 | Chemie (Z12) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E, F (A, H) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32437.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 549.7 | |
| All* | Total formula weight | 32987.4 |
