3FUC
Recombinant calf purine nucleoside phosphorylase in a binary complex with multisubstrate analogue inhibitor 9-(5',5'-difluoro-5'-phosphonopentyl)-9-deazaguanine structure in a new space group with one full trimer in the asymmetric unit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Purine nucleoside phosphorylase | polymer | 284 | 31687.1 | 3 | UniProt (P55859) Pfam (PF01048) | Bos taurus (Bovine) | PNP, Inosine phosphorylase |
| 2 | D, F, G (A, B, C) | [5-(2-amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)-1,1-difluoropentyl]phosphonic acid | non-polymer | 336.2 | 3 | Chemie (9D9) | |||
| 3 | E, H, I (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | J (C) | AZIDE ION | non-polymer | 42.0 | 1 | Chemie (AZI) | |||
| 5 | K, L, M (A, B, C) | water | water | 18.0 | 447 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 284 (UniProt: P55859)
| PDB | External Database | Details |
|---|---|---|
| Gln 2 | Ala 2 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 95061.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1123.6 | |
| All* | Total formula weight | 96185.0 |
