3FRF
S. aureus DHFR complexed with NADPH and iclaprim
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | X | Dihydrofolate reductase | polymer | 158 | 18144.7 | 1 | UniProt (P0A017) Pfam (PF00186) In PDB | Staphylococcus aureus | DHFR |
| 2 | X | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 3 | X | 5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine | non-polymer | 354.4 | 1 | Chemie (XCF) | |||
| 4 | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18144.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1099.8 | |
| All* | Total formula weight | 19244.6 |
